The Humans the Algorithms Can’t Reach

December 23, 2025

Pleio CEO Michael Oleksiw examines why, despite decades of digital innovation and billions invested, medication adherence remains stuck at 50%. Drawing on analysis of more than 140,000 patient conversations, he explores how the “Underminers” shape patient behavior and why the future of pharma depends on combining AI-driven insight with human connection to create lasting adherence.